Transcriptome analysis of Aspergillus niger xlnR and xkiA mutants grown on corn Stover and soybean hulls reveals a highly complex regulatory network
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چکیده
منابع مشابه
Transcriptome analysis of Aspergillus niger grown on sugarcane bagasse
BACKGROUND Considering that the costs of cellulases and hemicellulases contribute substantially to the price of bioethanol, new studies aimed at understanding and improving cellulase efficiency and productivity are of paramount importance. Aspergillus niger has been shown to produce a wide spectrum of polysaccharide hydrolytic enzymes. To understand how to improve enzymatic cocktails that can h...
متن کاملFunctional analysis of the transcriptional activator XlnR from Aspergillus niger.
The transcriptional activator XlnR from Aspergillus niger is a zinc binuclear cluster transcription factor that belongs to the GAL4 superfamily. Several putative structural domains in XlnR were predicted using database and protein sequence analysis. Thus far, only the functionality of the N-terminal DNA-binding domain has been determined experimentally. Deletion mutants of the xlnR gene were co...
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In this paper the dynamics of the transcription-translation system for XlnR regulon in Aspergillus niger is modeled. The simulations are based on Hill regulation functions and ordinary differential equations. The response to a single trigger of D-xylose to the system is considered, stability analysis is performed and the effects of activating and repressive feedback are also considered. Simulat...
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ژورنال
عنوان ژورنال: BMC Genomics
سال: 2019
ISSN: 1471-2164
DOI: 10.1186/s12864-019-6235-7